Abstract: The globalization operation of enterprises is changing the future of global economy. Enterprises of developing countries are not competitive in globalization innovation，but there are still a part of enterprises exploring the Ｒ＆D of global innovation，such as Huawei，the case enterprise in the paper. In this paper，the global innovation and model selection of high-tech innovation enterprises represented by Huawei are analyzed. In the aspects of product innovation and technology innovation，Huawei has developed to independent Ｒ＆D from agency，international advanced from imitation and follow，international leading from domestic leading，and global leading from international advanced; Huawei keeps stretching on both ends in global value chain，constantly makes global layout for preponderant capacity，and develops a unique successful innovative cooperative globalization road.